王立群，男，博士/博士后，副研究员，药理学硕士研究生导师。2013年获得南方医科大学医学博士学位；2013-2016年作为浙江大学/西南医科大学联合培养博士后在西南医科大学心血管医学研究所从事博士后研究工作；现为西南医科大学药物与功能性食品研究中心实验室主任。

研究方向：

细胞外基质对心血管功能的调控；

糖尿病心血管并发症的发病机理；

中国传统医药对心血管疾病的防治。

代表性论文：

1. Liqun Wang, Tangting Chen, Xiang Zhou, Qiaobing Huang, Chunhua Jin. Atomic force microscopy observation of lipopolysaccharide-induced cardiomyocytes cytoskeleton reorganization. Micon, 2013, 51: 48-53.

2. Liqun Wang, Haihua Luo, Xiaohuan Chen, Yong Jiang, Qiaobing Huang. Functional characterization of S100A8 and S100A9 in altering monolayer permeability of human umbilical endothelial cells. PloS One, 2014, 9 (3): e90472.

3. Liqun Wang, Xu Zhang, Ningbo Pang, Lamei Xiao, Yongjie Li, Ni Chen, Meiping Ren, Xin Deng, Jianbo Wu. Glycation of vitronectin inhibits VEGF-induced angiogenesis by uncoupling VEGF receptor-2-αvβ3 integrin cross-talk. Cell Death and Disease, 2015, 6: e1796.

4. Tangting Chen, Ni Chen, Ningbo Pang, Lamei Xiao, Yongjie Li, Rong Li, Mao Luo, Xin Deng, Meiping Ren, Jianbo Wu*,Liqun Wang*. Hydroxysafflor yellow A promotes angiogenesis via the angiopoietin 1/Tie-2 signaling pathway. J Vsac Res, 2016, 53 (5-6): 245-254.

5. Liqun Wang, Jie Wu, Xiaohua Guo, Xuliang Huang, Qiaobing Huang. RAGE plays a role in LPS-induced NF-κB activation and endothelial hyperpermeability. Sensors (Basel), 2017, 17 (4), pii: E722.

6. Ningbo Pang, Tangting Chen, Xin Deng, Ni Chen, Rong Li, Meiping Ren, Yongjie Li, Mao Luo, Haiyan Hao, Jianbo Wu*,Liqun Wang*. Polydatin prevents methylglyoxal-induced apoptosis through reducing oxidative stress and improving mitochondrial function in human umbilical vein endothelial cells, Oxid Med Cell Longev, 2017, 2017:7180943.

7. Jun Cheng^#, Tangting Chen^#, Jing Wen, Ningbo Pang, Liping Zhang,Liqun Wang.Sodium tanshinone IIA sulfonate prevents lipopolysaccharide-induced inflammation via suppressing nuclear factor-κB signaling pathway in human umbilical vein endothelial cells. Can J Physiol Pharmacol, 2018, 96(1):26-31.

8. Tangting Chen, Miaoling Li, Xuehui Fan, Jun Cheng,Liqun Wang. Sodium tanshinone IIA sulfonate prevents angiotensin II-Induced differentiation of human atrial fibroblasts into myofibroblasts, Oxid Med Cell Longev, 2018, 2018:6712585.

   主持的科研课题：

9. 国家自然科学基金面上项目：纤维连接蛋白糖基化介导的PDGF-BB信号激活障碍对糖尿病新生血管成熟不足的调控

10. 国家自然科学基金青年基金：糖基化纤维连接蛋白对血管内皮生长因子介导的血管新生的影响及其机制研究；

联系方式：

Email：yy000213@163.com；liqunwang@swmu.edu.cn;

电话：18113577900