王炳蔚,男,博士/博士后,副研究员,主要从事心血管与代谢调控的神经与分子机制研究。以第一/共同作者发表研究论文和综述文章30余篇。
教育与工作经历
2011.09 - 2015.06,内蒙古大学 生物科学 学士
2015.09 - 2021.01,北京大学 人体解剖与组织胚胎学 博士(导师:郑瑞茂研究员)
2021.01 - 2022.12,北京大学生物学博士后,合作导师:赵红珊教授,郑瑞茂研究员
2023.02 - 2024.02,美国宾夕法尼亚大学医学院博士后,合作导师:Prof. Lin Zhang
2024.03 - 至今,西南医科大学教育部代谢性心血管疾病医药基础研究创新中心,副研究员
研究方向
1.心血管与代谢调控的神经与分子机制
2.药用天然化合物的心血管调节作用研究
主持科研项目
1.中国博士后科学基金面上项目,8万,2022.06-2022.12,主持
代表性论文(#为并列第一作者,*为通讯作者)
1. Wang Bingwei#, Hu Zhiping#, Cui Long, Zhao Miao, Su Zhijie, Jiang Yong, Liu Jiarui, Zhao Yun, Hou Yujia, Yang Xiaoning, Zhang Chenyu, Guo Bingbing, Li Daotong, Zhao Liang, Zheng Shengmin, Zhao Yiguo, Yang Weipeng, Wang Dunfang, Yu Siwang, Zhu Shigong, Yan Yi, Yuan Geheng, Li Kailong, Zhang Wenqiang, Qin Lihua, Zhang Weiguang, Sun Feng, Luo Jianyuan, Zheng Ruimao*. βAR-mTOR-lipin1 pathway mediates PKA-RIIβ deficiency-induced adipose browning. THERANOSTICS, 2024; 14(13):5316-5335. (IF=12.4)
2. Wang Bingwei, Zhao Miao, Su Zhijie, Jin Baohua, Yang Xiaoning, Zhang Chenyu, Guo Bingbing, Li Jiebo, Hong Weili, Liu Jiarui, Zhao Yun, Hou Yujia, Lai Futing, Zhang Wei, Qin Lihua, Zhang Weiguang, Luo Jianyuan, Zheng Ruimao*. RIIβ-PKA in GABAergic Neurons of Dorsal Median Hypothalamus Governs White Adipose Browning. ADVANCED SCIENCE, 2023, 10(5): 2205173. (IF=17.5)
3. Wang Bingwei#, Yang Xiaoning#, Zhao Miao, Su Zhijie, Hu Zhiping, Zhang Chenyu, Guo Bingbing, Liu Jiarui, Qin Lihua, Zhang Weiguang, Zheng Ruimao*. Celastrol prevents high-fat diet-induced obesity by promoting white adipose tissue browning. CLINICAL AND TRANSLATIONAL MEDICINE, 2021, 11(12): e641. (IF=11.5)
4. Zhao Miao, Wang Bingwei, Zhang Chenyu, Su Zhijie, Guo Bingbing, Zhao Yun, Zheng Ruimao*. The DJ1-Nrf2-STING axis mediates the neuroprotective effects of Withaferin A in Parkinson's disease. CELL DEATH AND DIFFERENTIATION, 2021, 28(8): 2517-2535. (IF=15.8)
5. Guo Bingbing#, Liu Jiarui#, Wang Bingwei, Zhang Chenyu, Su Zhijie, Zhao Miao, Qin Lihua, Zhang Weiguang, Zheng Ruimao*. Withaferin A Promotes White Adipose Browning and Prevents Obesity Through Sympathetic Nerve-Activated Prdm16-FATP1 Axis. DIABETES, 2022, 71(2): 249-263. (IF=9.4)
6. Zhang Chenyu#, Zhao Miao#, Wang Bingwei, Su Zhijie, Guo Bingbing, Qin Lihua, Zhang Weiguang, Zheng Ruimao*. The Nrf2-NLRP3-caspase-1 axis mediates the neuroprotective effects of Celastrol in Parkinson's disease. REDOX BIOLOGY, 2021, 47: 102134. (IF=11.8)
7. Zhang Jingliang#, Zhang Chenyu#, Chen Xiaoling, Wang Bingwei, Ma Weining, Yang Yang, Zheng Ruimao*, Huang Zhuo*. PKA-RIIβ autophosphorylation modulates PKA activity and seizure phenotypes in mice. COMMUNICATIONS BIOLOGY, 2021, 4(1): 263. (IF=6.3)
8. XiaomengWang#, XiaotongWu#, Hao Wu, Hanyang Xiao, Sijia Hao, Bingwei Wang, ChenLi, KatherinBleymehl, StefanG. Kauschke, Volker Mack, BorisFerger, HolgerKlein, RuimaoZheng, ShuminDuan, Hao Wang*. Neural adaption in midbrain GABAergic cells contributes to high-fat diet–induced obesity. SCIENCE ADVANCES. 9,eadh2884(2023). (IF=13.6)
9. Youyou Zhang#, Mu Xu#, Jiao Yuan, Zhongyi Hu, Junjie Jiang, Jie Huang, Bingwei Wang, Jianfeng Shen, Meixiao Long, Yi Fan, Kathleen T. Montone, Janos L. Tanyi, Omid Tavana, Ho Man Chan, Xiaowen Hu*, Lin Zhang*. Repression of PRMT activities sensitize homologous recombination-proficient ovarian and breast cancer cells to PARP inhibitor treatment. eLife 13:RP99225 (2025) (IF=6.4)
联系方式
西南医科大学城北校区双创楼904-4
E-mail:bw.wang@swmu.edu.cn