郑有坤，男，博士/博士后，副研究员，硕士生导师，主要从事生物功能材料的组装及医学应用。以第一作者或通讯作者在SCI期刊上发表论文10余篇。
教育工作经历
2009.09-2013.06，四川农业大学 农业资源与环境，学士
2013.09-2016.06，云南大学 微生物学，硕士(导师：徐丽华)
2016.09-2019.06，东南大学 生物医学工程，博士(导师：王雪梅)
2019.07-2020.12，西南医科大学药物与功能性食品研究中心，助理研究员
2021.01-至今，西南医科大学药物与功能性食品研究中心，副研究员，浙江大学-西南医科大学心血管医学研究所博士后(药学，导师：凌代舜/吴剑波)
研究方向
1. 纳米生物学：纳米药物与细胞的界面效应与调控
2. 具有创面修复功能生物材料的设计与组装
主要研究项目
1.四川省自然科学基金面上项目，20万，2022.01-2023.12，主持
2.中国博士后科学基金面上项目，8万，2022.01-2023.12，主持
3.四川省卫生健康委医学科技项目，5万，2022.01-2023.12，主持
代表性论文（#为并列第一作者，*为通讯作者）
1. Zheng Youkun#, Wei Min#, Wu Haibin, Li Fangyuan*, Ling Daishun*. Antibacterial metal nanoclusters.Journal of Nanobiotechnology, 2022, 20(1): 1-19. (IF=9.429)
2. Qin Zhaojian#, Zheng Youkun#, Du Tianyu, Wang Yihan, Gao Haiming, Wang Xuemei*, Jiang Hui*. Burst release of antibacterial clusters from gold-silver nanoboxes triggered by carboxylates modulating electron compensation effect.Chemical Engineering Journal, 2022, 450, 138322. (IF=16.744)
3. Zheng Youkun*, Wu Jianbo, Jiang Hui, Wang Xuemei*. Gold nanoclusters for theranostic applications.Coordination Chemistry Reviews2021, 431, 213689. (IF=24.833)
4. Tang Zonghao#, Liu Shuyun#, Chen Ni, Luo Mao, Wu Jianbo*, Zheng Youkun*. Gold nanoclusters treat intracellular bacterial infections: eliminating phagocytic pathogens and regulating cellular immune response.Colloids and Surfaces B: Biointerfaces2021, 205, 111899. (IF=5.999)
5. Qin Zhaojian#, Zheng Youkun#, Du Tianyu, Wang Yihan, Gao Haiming, Quan Jinfeng, Zhang Ying, Du Ying, Yin Lihong, Wang Xuemei*, Jiang Hui*. Cysteamine: A key to trigger aggregation-induced NIR-II photothermal effect and silver release booming of gold-silver nanocagesfor synergetic treatment of multidrug-resistant bacteria infection.Chemical Engineering Journal2021, 414, 128779. (IF=16.744)
6. Zheng Youkun, Jiang Hui*, Wang Xuemei*. Facet-dependent antibacterial activity of Au nanocrystals.Chinese Chemical Letters2020, 31(12), 3183−3189. (IF=8.455)
7. Zheng Youkun, Liu Weiwei, Chen Yun, Li Chunmei, Jiang Hui*, Wang Xuemei*. Conjugating gold nanoclusters and antimicrobial peptides: From aggregation-induced emission to antibacterial synergy.Journal of Colloid and Interface Science2019, 546, 1−10. (IF=9.965)
8. Zheng Youkun, Wang Xuemei*, Jiang Hui*. Label-free detection ofAcinetobacter baumanniithrough the induced fluorescence quenching of thiolated AuAg nanoclusters.Sensors and Actuators B: Chemical2018, 277, 388−393. (IF=9.221)
9. Zheng Youkun, Liu Weiwei, Chen Yun, Jiang Hui*, Wang Xuemei*. Mercaptopyrimidine directed gold nanoclusters: a sutable fluorescent probe for intracellular glutathione imaging and selective cancer cell identification.Journal of Materials Chemistry B2018, 6, 3650−3654. (IF=7.571)
10. Zheng Youkun, Liu Weiwei, Qin Zhaojian, Chen Yun, Jiang Hui*, Wang Xuemei*. Mercaptopyrimidine-conjugated gold nanoclusters as nanoantibiotics for combating multidrug-resistant superbugs.Bioconjugate Chemistry2018, 29, 3094−3103. (IF=6.069)
11. Hu Xueqi#, Zheng Youkun#, Zhou Junyu, Fang Danjun, Jiang Hui*, Wang Xuemei*. Silver-assisted thiolate ligand exchange induced photoluminescent boost of gold nanoclusters for selective imaging of intracellular glutathione.Chemistry of Materials2018, 30, 1947−1955. (IF=10.508)
12. Zheng Youkun, Liu Weiwei, Chen Yun, Jiang Hui, Yan Hong, Kosenko Irina, Chekulaeva Lubov, Sivaev Igor, Bregadze Vladimir, Wang Xuemei*. A highly potent antibacterial agent targeting methicillin-resistantStaphylococcus aureusbased on cobalt bis(1,2-dicarbollide) alkoxy derivative.Organometallics2017, 36, 3484-3490. (IF=3.837)
13. Zheng Youkun, Miao Cuiping, Chen Huahong, Huang Fangfang, Xia Yumei, Chen Youwei, Zhao Lixing*. Endophytic fungi harbored inPanax notoginseng: diversity and potential as biological control agents against host plant pathogens of root-rot disease.Journal of Ginseng Research, 2017, 4: 353-360. (IF=5.735)
招生计划
药理学1人，药学1人
联系方式
西南医科大学城北校区科技大楼802
E-mail：zyktmx@163.com
